My Cart [ 0 ]
Home > Proteins & Peptides > A-Z Proteins  > IL-5 Protein

IL-5 Protein

Interleukin-5, EDF, BCDFII, TRF, T-cell replacing factor, Eosinophil differentiation factor, B cell differentiation factor I

Catalog No. Product Name Size List Price (US$) Quantity
BP000158-CYT-212 Recombinant Human IL-5 10 ug 160.00
BP000158-CYT-212 Recombinant Human IL-5 1 mg 3870.00
Description

Introduction
The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

BP000158-CYT-212: Recombinant Human IL-5

Source: E. coli-derived.
A dimeric, non-glycosylated polypeptide chain containing 132 amino acids and having a molecular mass of 26522.84 Dalton.
N-terminal sequence analysis: Met-Ile-Pro-Thr-Glu.
The ED50 as determined by the dose-dependant stimulation of the proliferation of TF-1 cells was found to be < 0.15 ug/ml, corresponding to a Specific Activity of 6.7 MIU/mg.
Purity > 98%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Interleikin-5 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other IL-5 Proteins:
Recombinant Mouse IL-5
Recombinant Rat IL-5

IL-5 ELISA Kits:
Mouse IL-5 ELISA Kit
Human IL-5 ELISA Kit

Related Links

See our Privacy Policy