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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal IL-19 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
IL19 is a cytokine that belongs to the IL10 cytokine subfamily. IL-19 is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
BP000143-CYT-363: Recombinant Human IL-19
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 155 amino acids and having a molecular mass of 17913 Dalton.
N-terminal sequence analysis: Met-Leu-Arg-Arg-Cys.
The activity is determined by it's ability to activate STAT following receptor-ligand interaction.
Purity > 99%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing 10 mM sodium citrate pH-5.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-19 in sterile 18 M?-cm H2O at a concentration of 0.5 ug/ml or less.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other IL-19 Protein:
Recombinant Mouse IL-19
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