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Home > Proteins & Peptides > A-Z Proteins  > IL-19 Protein

IL-19 Protein

Interleukin-19, Melanoma differentiation association like protein, MDA1, NG.1, ZMDA1, IL-10C

Catalog No. Product Name Size List Price (US$) Quantity
BP000143-CYT-363 Recombinant Human IL-19 10 ug 160.00
BP000143-CYT-363 Recombinant Human IL-19 1 mg 4680.00
Description

Introduction
IL19 is a cytokine that belongs to the IL10 cytokine subfamily. IL-19 is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.

BP000143-CYT-363: Recombinant Human IL-19

Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 155 amino acids and having a molecular mass of 17913 Dalton.
N-terminal sequence analysis: Met-Leu-Arg-Arg-Cys.
The activity is determined by it's ability to activate STAT following receptor-ligand interaction.
Purity > 99%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing 10 mM sodium citrate pH-5.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-19 in sterile 18 M?-cm H2O at a concentration of 0.5 ug/ml or less.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other IL-19 Protein:
Recombinant Mouse IL-19

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