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CCL26 Protein

C-C Motif Chemokine 26, TSC-1, SCYA26, Eotaxin-3, MIP-4-Alpha, Small-Inducible Cytokine A26, CC Chemokine IMAC

Catalog No. Product Name Size List Price (US$) Quantity
BP000264-CHM-362 Recombinant Human CCL26 Protein 50 ug 160.00
BP000264-CHM-362 Recombinant Human CCL26 Protein 1 mg 1800.00
Description

Introduction
Eotaxin-3 (CCL26) is a small cytokine that belongs to the CC chemokine family also known as TARC (thymus and activation regulated chemokine). CCL26 is major eotaxin produced and released by alveolar epithelial cells which is involved in autoregulation of CCR3 receptors and other eotaxins. Eotaxin-3 is involved in immunoregulatory and inflammatory processes. Eotaxin-3 specifically binds and stimulates chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26 exhibits chemotactic activity for normal peripheral blood eosinophils and basophils. Eotaxin-3 may play a part in the eosinophil accumulation in atopic diseases. Eotaxin-3 is overexpressed in eosinophilic esophagitis, and the expression level correlates with disease severity. Eotaxin-3 is expressed constitutively in thymus, but only briefly in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL26 is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7.

BP000264-CHM-362: Recombinant Human C-C Motif Chemokine 26 (CCL26) Protein

Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 72 amino acids (24-94 a.a.) and having a total molecular mass of 8.5 kDa.
Purity: > 90% by SDS-PAGE.
Formulation: The Eotaxin-3 solution contains Phosphate Buffered Saline pH 7.4 and 10% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other CCL26 Proteins:
Recombinant Human CCL26 (27-94) Protein
Recombinant Human CCL26 (24-94) Protein

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