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A full range of bioanalysis services for basic research, non-clinical and clinical studies.
    14 Bioanalytical Services
  • Sample requirement: 50-100 ug.

    Fast turnaround time: 1 - 2 weeks.

  • The antibody variable regions of both heavy chain (VH) and light chain (VL) are analyzed for liabilities including, but not limited to N-linked glycosylation, deamidation, isomerization, pyroglutamate formation, and oxidation.

    Fast turnaround time: 1 week per antibody, but may require more time depending on the complexity of analysis.

  • N-terminal Edman sequencing of proteins or peptides can be used to determine the N-terminal amino acid residues of purified protein samples in addition to cleavage sites, and to identify an unknown protein or confirm the identity of a known protein, or to design oligonucleotide probes.

    High sensitivity: even with picomoles of protein.

    Various formats: in solution, gels or on PVDF blots.

    Fast turnaround time: 1-2 weeks per sample, but may require more time depending on the complexity of analysis.

  • Kinetic analysis is used to determine the affinity of an antibody to its soluble antigen using surface plasmon resonance (SPR) or biolayer interferometry (BLI), which can measure kon, koff, and kD. Association and dissociation are measured on the Biacore T100 or the ForteBio Octet QKe using various concentrations of the antigen and the kD is calculated using an appropriate curve-fitting model.

    Fast turnaround time: 2-3 days per antibody-antigen pair, but may require more time depending on the complexity of analysis.

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